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Ipertermia nelle recidive del cancro del seno

Ipertermia si rivela efficace nella recidiva local del tumore della mammella

ricercaL'ipertermia oncologica si dimostra ottimo coadiuvante nelle recidive locoregionali di tumore mammario.





Dr. Carlo Pastore

World J Surg Oncol. 2012 Sep 27;10(1):201. [Epub ahead of print]

The utility of hyperthermia for local recurrence of breast cancer.

Yamamoto D, Inui T, Tsubota Y, Sueoka N, Yamamoto C, Kuwana K, Yamamoto M.



BACKGROUND: Hyperthermia has long been used in combination with chemotherapy or radiation therapy for the treatment of superficial malignancies, in part due to its sensitizing capabilities. Patients who suffer from superficial recurrences of breast cancer have poor clinical outcomes. Skin metastases may particularly impair the quality of life due to the physical appearance, odor and bleeding.


A 66-year-old woman underwent mastectomy and axillary lymph node dissection for breast cancer. Nine years post-operatively, local metastases developed in the left axillary area (measuring 5 cm in diameter). Initially the tumor did not respond to radiation therapy and chemotherapy. Therefore, we added hyperthermia combined with them. Eight weeks later, the tumor became nearly flat and the patient noted improved activity in her daily life.


Hyperthermia may accelerate the antitumor effects of radiation therapy and chemotherapy. This treatment provides an alternative for unresectable breast cancer skin metastases.

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