Criochirurgia ed Ipertermia nel controllo delle metastasi cutanee
In questo studio viene riportato un caso di successo nel trattamento di ampie metastasi cutanee da tumore mammario. La combinazione adottata è criochirurgia ed ipertermia locoregionale.
Dr. Carlo Pastore
Int J Surg Case Rep. 2012;3(2):68-9. Epub 2011 Nov 10.
Hachisuka J, Doi K, Furue M.
Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Skin metastases may impair the quality of life due to physical appearance, odour, and bleeding. PRESENTATION OF
A 70-year-old woman presented with two enlarging nodules (measuring 12 cm and 3 cm in diameter) consistent with metastatic breast cancer in the left subclavicular area. The larger tumour did not respond to initial cryosurgery. Therefore we added hyperthermia using a disposable body warmer. In addition, the cryosurgery technique was modified to freeze deeper tissue. The entire tumour was covered with dry cotton, to which liquid nitrogen was applied. Twenty weeks later, the tumour became nearly flat and the patient noted improved activity in her daily life.
Combination treatment with sufficient freezing is important for controlling the tumour, while hyperthermia may accelerate the antitumor effects of cryosurgery. CONCLUTION: This treatment provides an alternative for unresectable breast cancer skin metastases resistant to chemotherapy and radiotherapy.